What effect do beta-blockers have on heart rate?

Beta-blockers, also known as beta-adrenergic antagonists, primarily function by blocking the effects of adrenaline on beta-adrenergic receptors in the heart. This action leads to a reduction in heart rate, which is advantageous in various clinical scenarios, such as hypertension, heart failure, and certain arrhythmias. By decreasing the heart rate, beta-blockers allow the heart to work more efficiently and reduce the overall workload on the cardiovascular system. This mechanism is crucial for managing conditions where decreased heart rate can contribute to better outcomes, such as in reducing the risk of angina and improving heart function in heart failure patients.