Which antihypertensive medication can be administered via a transdermal patch?

Clonidine is the antihypertensive medication that can be administered via a transdermal patch. This method of delivery allows for a sustained release of the drug over time, which helps in managing blood pressure while providing a more convenient and consistent way for patients to adhere to their medication regimen.

The transdermal patch is particularly beneficial for clonidine because it enables a continuous absorption of the drug, helping to maintain steady blood levels and reducing the incidence of side effects associated with peak doses. This is particularly important in treating hypertension, where maintaining consistent blood pressure levels is crucial for effective management.

Other antihypertensive medications mentioned, such as amlodipine, candesartan, and enalapril, are typically available in oral formulations and do not have transdermal patch options available. Amlodipine and enalapril are both standard medications for hypertension, used orally to achieve therapeutic effects; however, their pharmacokinetics do not support transdermal delivery methods. Candesartan, being an angiotensin receptor blocker, also does not come in a transdermal form as of the current knowledge base. Therefore, the unique transdermal delivery of clonidine distinguishes it from the other options presented.