Which medication class may reduce blood pressure by inhibiting angiotensin II?

The medication class that reduces blood pressure by inhibiting angiotensin II is ACE inhibitors. These drugs work by blocking the enzyme angiotensin-converting enzyme (ACE), which is responsible for converting angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor, and it also stimulates the release of aldosterone, leading to increased sodium and water retention, which contributes to higher blood pressure. By inhibiting ACE, these medications decrease the levels of angiotensin II in the bloodstream, resulting in vasodilation and a reduction in blood pressure.

This mechanism is critical to managing hypertension and protecting against cardiovascular events, making ACE inhibitors a cornerstone in the treatment of high blood pressure. Overall, the ability of ACE inhibitors to directly affect the renin-angiotensin system underlines their effectiveness in lowering blood pressure safely and efficiently.