Which patient is most likely to be at risk for neutropenia while on captopril?

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Captopril is an ACE (angiotensin-converting enzyme) inhibitor commonly used to treat hypertension and heart failure. One of the potential side effects of captopril is neutropenia, which is a significant decrease in neutrophils, a type of white blood cell essential for fighting infections.

Impaired renal function can lead to alterations in drug metabolism and clearance, increasing the risk of side effects such as neutropenia. When the kidneys are not functioning optimally, they may be unable to effectively process and eliminate the medication from the system, potentially leading to higher drug levels and an increased risk of adverse reactions.

Patients with impaired renal function need careful monitoring and dosage adjustments, as the risks associated with captopril, including the development of neutropenia, are greater in this population. Thus, Mark is the patient most likely to be at risk for developing neutropenia while on captopril due to his renal issues.

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